Pregnancy, lactation, hypersensitivity to iloprost or to any of the other ingredients.
Conditions where the effects of Ilomedin 20 on platelets might increase the risk of hemorrhage (e.g. active peptic ulcers, trauma, intracranial hemorrhage).
Severe coronary heart disease or unstable angina; myocardial infarction within the last six months; acute or chronic congestive heart failure (NYHA II-IV); severe arrhythmias; suspected pulmonary congestion.